Boehringer Ingelheim and OSE Immunotherapeutics agree cancer research alliance

Boehringer Ingelheim has announced a new collaboration with OSE Immunotherapeutics that will aim to jointly develop a new immuno-oncology therapy.

The exclusive worldwide collaboration and licence agreement will focus on the development of OSE-172, a SIRP-alpha antagonist targeting myeloid lineage cells, which could be used for the treatment of advanced solid tumours.

OSE-172 has the potential to enhance anti-tumour immunity by improving T cell activity, and is currently in late-stage preclinical development. It has shown potential benefits in the treatment of multiple cancer types.

Boehringer Ingelheim has acquired global rights to develop, register and commercialise OSE-172, with OSE Immunotherapeutics to receive a EUR 15 million (GBP 13.1 million) upfront payment, as well as more than EUR 1.1 billion based on the achievement of certain milestones.

Dr Jonathon Sedgwick, global head of cancer immunology and immune modulation research at Boehringer Ingelheim, said: "We are dedicated to developing groundbreaking, first-in-class therapies that can transform the lives of patients and help win the fight against cancer."

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