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Home Industry News Bristol-Myers Squibb and Incyte to launch new cancer drug trials

Bristol-Myers Squibb and Incyte to launch new cancer drug trials

5th April 2017

Bristol-Myers Squibb and Incyte have announced plans to take their new combination therapy of Opdivo and epacadostat into first-line registrational trials.

The companies will advance their clinical development programme evaluating the combination of epacadostat and Opdivo into phase III registrational studies in first-line non-small cell lung cancer across the spectrum of PD-L1 expression, as well as first-line head and neck cancer.

Additionally, the companies are expanding the ECHO-204 phase I/II study, established under a collaboration between the companies in 2014, to include anti-PD-1/PD-L1 relapsed/refractory melanoma cohorts.

The expanded clinical development programme including the phase III registrational studies, will be co-funded by both partners and will help bring them a step closer to delivering new and improved treatment options for a range of cancers.

Dr Fouad Namouni, head of development for oncology at Bristol-Myers Squibb, said: "Incyte shares our goal of improving clinical outcomes for patients with some of the hardest-to-treat cancers, and we look forward to working together on studies evaluating the clinical outcomes of this therapeutic combination."

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