Bristol-Myers Squibb’s Opdivo shows benefits in treatment of melanoma

Bristol-Myers Squibb has reported the findings of a new clinical trial that demonstrate the benefits its drug Opdivo can offer to melanoma patients.

Data from the CheckMate-238 phase III trial have shown that Opdivo was able to deliver a better performance in patients with stage IIIb/c or stage IV melanoma who were at high risk of recurrence following complete surgical resection than the company's older drug Yervoy.

Opdivo met its primary endpoint at a planned interim analysis by demonstrating superior recurrence-free survival rates in patients compared to Yervoy, with data from this study to be submitted for presentation at an upcoming medical conference.

Presently, there remains an unmet need for additional options for this condition, as the majority of stage III and resected stage IV high-risk melanoma patients experience disease recurrence after surgery.

Dr Vicki Goodman, development lead for melanoma and genitourinary cancers at Bristol-Myers Squibb, said: "We are committed to researching therapies that may better meet the needs of this patient population and look forward to sharing these data with health authorities soon."

The drug was approved by the European Commission as a treatment for urothelial carcinoma last month.

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