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Home Industry News Celgene and Evotec announce neurodegenerative disease research collaboration

Celgene and Evotec announce neurodegenerative disease research collaboration

16th December 2016

Celgene has announced a new collaboration with Evotec that aims to develop new treatments for a range of neurodegenerative diseases.

The strategic drug discovery and development alliance will identify disease-modifying therapeutics, with an initial focus on amyotrophic lateral sclerosis, Alzheimer's disease, Parkinson's disease and multiple other conditions.

This will leverage Evotec's iPSC infrastructure, which has been developed over the last five years to industrialise iPSC-based drug screening in terms of throughput, reproducibility and robustness in collaboration with Harvard University.

Evotec will receive an upfront payment of $45 million (36.16 million pounds) under the terms of the deal and may be eligible to receive up to $250 million in milestone-related fees, as well as double-digit royalties on in-licensed programmes.

Celgene will receive exclusive options to in-license worldwide rights to Evotec programmes developed from the company's compound library, and may also elect to screen compounds from its proprietary CELMoD library using Evotec's iPSC platform.

Dr Rupert Vessey, executive vice-president and president of research and early development of Celgene, said: "We are very pleased to enter into our first neurodegeneration collaboration with Evotec and look forward to the screening of their compound libraries using their proprietary iPSC platform."

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