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Fertility problems ‘can be passed on by men to their sons’
A new study has indicated that infertility problems among males can often be passed on to their male offspring.
Led by the Centre for Reproductive Medicine at the Vrije Universiteit Brussel, the research focused on the world's oldest group of young men conceived by means of a fertility treatment known as intracytoplasmic sperm injection (ICSI).
Looking at 54 men, born in the early years of ICSI between 1992 and 1996, it was found that the men had almost half the sperm concentration and a twofold lower total sperm count and total count of motile sperm than naturally conceived men of a similar age.
Additionally, compared to men born after spontaneous conception, ICSI-born men were nearly three times more likely to have sperm concentrations below 15 million per millilitre of semen, and four times more likely to have total sperm counts below 39 million.
Professor Andre Van Steirteghem, one of the co-authors of this study, said: "These first results from the oldest group of ICSI-conceived adults worldwide indicate that a degree of 'sub-fertility' has, indeed, been passed on to sons of fathers who underwent ICSI because of impaired semen characteristics."
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