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Home Industry News Integrated DNA Technologies earns praise for xGEN Lockdown Probes

Integrated DNA Technologies earns praise for xGEN Lockdown Probes

14th August 2013

Integrated DNA Technologies has helped scientists at the University of Texas at Austin achieve numerous research breakthroughs through the use of its xGEN Lockdown Probes.

Researchers at Professor Jeffrey Barrick's laboratory at the university have been using the probes for the target enrichment of specific gene regions, as they seek to create methods of tracking rare mutations in evolving populations in order to assess their effects on fitness.

Thanks to the xGEN Lockdown Probes, the team was able to obtain a greater depth of coverage, sequencing only the regions of interest, thus reducing the total volume of data they collected and minimising analysis time.

The manufacturer's probes are individually synthesised and assessed by mass spectroscopy for quality control, thus enabling a seamless transition from discovery to clinical application.

Dr Daniel Deatherage, a postdoctoral associate at the laboratory, said: "One of the nice things about the probes is that we could start from a single biotinylated probe and expand to a whole pool of the xGEN Lockdown Probes."

This comes after Integrated DNA Technologies recently announced the launch of a new manufacturing facility in Singapore, part of its efforts to expand its global capabilities.ADNFCR-8000103-ID-801625052-ADNFCR

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