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Home Industry News Lilly and Nektar Therapeutics to develop new autoimmune therapy

Lilly and Nektar Therapeutics to develop new autoimmune therapy

25th July 2017

Lilly has announced a new partnership with Nektar Therapeutics that will focus on the development of a new immunology treatment.

The strategic collaboration will see the companies working to co-develop NKTR-358, a novel immunological therapy discovered by Nektar. This compound has the potential to treat a number of autoimmune and other chronic inflammatory conditions.

Having achieved a first human dose with the drug in phase I clinical development during March 2017, Nektar will receive an initial payment of $150 million (115.06 million pounds) to co-develop NKTR-358 with Lilly.

Nektar will be responsible for completing phase I clinical development, with both parties sharing phase II development costs. Nektar will then have the option to participate in phase III development on an indication-by-indication basis.

Dr Thomas Bumol, senior vice-president of biotechnology and immunology research at Lilly, said: "NKTR-358 is an exciting addition to our immunology portfolio and reinforces Lilly's commitment to sustain a flow of innovative medicines in our pipeline."

The compound is a potential first-in-class resolution therapeutic that may address underlying immune system imbalances by targeting the interleukin receptor complex in the body to stimulate proliferation of powerful inhibitory immune cells known as regulatory T cells.

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