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Nanotechnology-based test facilitates rapid Zika virus diagnosis
US researchers have developed a new nanotechnology-based approach to creating a rapid diagnostic test for the Zika virus.
A team from the Washington University School of Medicine and the School of Engineering and Applied Science created a test that incorporates a protein made by the Zika virus that causes an immune response in infected individuals.
This protein was then attached to tiny gold nanorods mounted on a piece of paper, which was subsequently completely covered with tiny, protective nanocrystals that allow the test to be shipped and stored without the need for refrigeration.
Applying a blood sample to the paper produces a reaction that can be identified within 15 minutes, with no false-positive results observed in initial tests. The assay is low-cost, and can be easily distributed to low-resource areas.
Dr Jeremiah Morrissey, a research professor of anaesthesiology at Washington University, said: "With this test, results will be clear before the patient leaves the clinic, allowing immediate counseling and access to treatment."
The team will now determine whether this approach will also work with other emerging infectious diseases, or whether it could be applied to saliva rather than blood.
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