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Home Industry News New blood test ‘could help predict breast cancer relapses’

New blood test ‘could help predict breast cancer relapses’

27th August 2015

UK researchers have developed a means of potentially predicting breast cancer relapses through the use of a blood test.

A team from the Institute of Cancer Research in London and the Royal Marsden NHS Foundation Trust have found a means of tracking mutations that cancer accumulates as it develops and spreads without the need for invasive biopsies.

Tumour and blood samples were taken from 55 breast cancer patients with early-stage disease who had received chemotherapy followed by surgery, with the individuals then monitored with blood tests taken after surgery and then every six months in follow-up.

Women who tested positive for circulating tumour DNA were 12 times more likely to experience a relapse than those who tested negative, with the return of the cancer detected an average of 7.9 months before any visible signs emerged.

By analysing the DNA code found in blood samples, it may also be possible to identify particular mutations likely to prove lethal to that patient, and tailor treatment accordingly.

Study leader Dr Nicholas Turner, team leader in molecular oncology at the Institute of Cancer Research, said: "It will be some years before the test could potentially be available in hospitals, but we hope to bring this date closer by conducting much larger clinical trials starting next year."ADNFCR-8000103-ID-801798961-ADNFCR

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