New method for halting spread of breast cancer identified

A new study has identified a potentially promising novel method of halting the spread of breast cancer.

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore has indicated that controlling the levels of a protein called TIP60 – a tumour suppressor – could potentially help to prevent the spread of breast cancer cells.

TIP60 was shown to interact with two other proteins called DNMT1 and SNAIL2 to inhibit metastasis, the process by which cancer cells spreads to other parts of the body. In breast cancer patients with poor survival prognoses, TIP60 levels tend to be low.

Sudhakar Jha, an assistant professor at the university, said: "This study provides important evidence that TIP60 levels could possibly serve as prognostic marker of breast cancer progression, and the stabilisation of TIP60 could be a promising strategy to treat cancers."

Future research could examine ways of using drugs to increase TIP60 levels and prevent the spread of cancer. This could also have positive implications for people with colon and cervical cancers, which have also been found to be associated with irregular TIP60 levels.

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