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Home Industry News New study underlines link between smoking and mortality risk in men

New study underlines link between smoking and mortality risk in men

5th December 2014

New research from Sweden has provided further evidence of the link between smoking and a higher mortality risk in men.

Scientists at Uppsala University have demonstrated an association between smoking and loss of the Y chromosome in blood cells, having previously linked the loss of the Y chromosome to a heightened cancer risk in a previous study.

This chromosome damage was more common in heavy smokers compared to moderate smokers, while the trend was only valid for men who were current smokers. Men who had quit the habit showed the same frequency of Y chromosome loss as men who had never smoked.

The mechanism behind this observation are currently unclear, but it is thought that immune cells in blood that have lost their Y chromosome may have a reduced capacity to fight cancer cells.

Jan Dumanski, professor at the department of immunology, genetics and pathology at Uppsala University, said: "This finding may in part explain why men in general have a shorter lifespan than women and why smoking is more dangerous for men."

Recently-published UK government data has shown a dramatic fall in the number of smokers since the 1970s, thanks in part to wider awareness of its health impact.ADNFCR-8000103-ID-801764630-ADNFCR

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