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Noninvasive tissue scanner ‘could aid treatment of psoriasis’
An innovative handheld tissue scanner has been developed that could represent a considerable step forward for the understanding and treatment of psoriasis.
Researchers from Helmholtz Zentrum Munchen and the Technical University of Munich created a system that allows clinically relevant information on the structure of skin layers and blood vessels to be extracted without the need for contrast agents or radiation exposure.
It uses a weak laser pulse to stimulate the tissue, which then absorbs energy and experiences a small increase in heat. This in turn causes momentary tissue expansion that generates ultrasound waves, which can be measured to create a high-resolution image.
The system has been shown to be effective in determining several characteristics of psoriasis and inflammation, including skin thickness, capillary density, the number of vessels, and total blood volume in the skin.
Professor Dr Vasilis Ntziachristos, director of the Institute of Biological and Medical Imaging at the Helmholtz Zentrum Munchen, said: "This technology, which is easy to use and does not involve any radiation exposure or contrast agent, is allowing us to acquire the first new insights into the disease mechanisms. It also facilitates treatment decisions for physicians."
It is hoped that the same technology can be used to assess other diseases, such as skin cancer or diabetes, in the future.
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