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Home Industry News Novartis and UC Berkeley announce new disease research alliance

Novartis and UC Berkeley announce new disease research alliance

29th September 2017

Novartis has announced a new collaboration with the University of California, Berkeley with the aim of creating new therapies for hard-to-treat conditions.

A new facility called the Novartis-Berkeley Center for Proteomics and Chemistry Technologies will be established at existing labs in Berkeley to develop new technologies for the discovery of next-generation therapeutics.

The overarching aim of the study will be to find new treatments for a large number of disease targets in cancer and other illnesses that have proven "undruggable" with traditional small-molecule therapy approaches.

Joint research projects between Novartis and UC Berkeley scientists will harness covalent chemoproteomics technology that rapidly maps locations on protein targets where compounds could form lasting bonds, providing starting points for novel therapeutics.

Efforts will also be made to explore the potential of emerging degrader therapeutics, screening natural product compounds and using covalent chemoproteomics to discover targets, understanding mechanisms of action and develop new platform technology.

Jay Bradner, president of the Novartis Institutes for BioMedical Research, said: "Our Berkeley alliance powerfully extends our ability to advance discovery of molecules aimed at the historically inaccessible drug targets."

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