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Home Industry News Roche launches Avenio circulating tumour DNA analysis kits

Roche launches Avenio circulating tumour DNA analysis kits

10th May 2017

Roche has announced the global commercial launch of its new Avenio circulating tumour DNA (ctDNA) analysis kits.

The range consists of three next-generation sequencing liquid biopsy assay kits for oncology research, including the Avenio ctDNA Targeted Kit, Expanded Kit and Surveillance Kit. All three include reagents, bioinformatics and software needed to conduct ctDNA testing.

With the Targeted Kit, researchers gain access to a 17-gene pan-cancer assay for identifying guideline-related biomarkers, with the Expanded Kit covering 77 genes, including emerging biomarkers. Meanwhile, the Surveillance Kit contains 197 genes and is optimised to longitudinally monitor tumour burden in lung and colorectal cancer.

These new kits can be used to detect all four mutation classes with high levels of sensitivity, with the different options allowing researchers to profile the genomic complexities of different cancer stages and tumour types and generate results in five days.

Roche's proprietary error-suppression strategies enable the Avenio kits to detect variant allele frequencies down to 0.1 percent, while maintaining a low error rate of as low as 0.001 percent.

Roland Diggelmann, chief executive officer of Roche Diagnostics, said: "Roche believes the Avenio ctDNA assays can help researchers around the world advance personalised oncology by enabling them to carry out their own testing."

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