Looks like you’re on the UK site. Choose another location to see content specific to your location

Home Industry News Study reveals new insight into genetic causes of bipolar disorder

Study reveals new insight into genetic causes of bipolar disorder

24th February 2011

A newly-published study has highlighted the potential role played by a brain protein in increasing the genetic risk of bipolar disorder.

According to the research in the medical journal Biological Psychiatry, the gene coding of the protein known as Piccolo – which contributes to the ability of nerve cells to release chemicals – could be linked to inheritance of the mental condition.

By comparing gene expression patterns in post-mortem cortical tissue among a number of subjects, it was found that a marker for Piccolo, SNP rs13438494, had altered expression levels among those diagnosed with bipolar disorder.

Study leader Dr Kwang Choi said these findings could confirm a link between gene expression and genome-wide association studies, provided that they can be replicated.

Dr John Krystal, editor of Biological Psychiatry, added: "This study is an example of how better knowledge of brain biology may help to guide our genetics studies."

According to NHS statistics, bipolar disorder is a relatively common condition in the UK that affects one person in every 100.ADNFCR-8000103-ID-800426278-ADNFCR

We currently have 9 jobs available in Pharmacy industry, find your perfect one now.

Stay informed

Receive the latest industry news, Tips
and straight to your inbox.