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Home Industry News Pharmaceutical Merck Gains FDA Approval for Endometrial Cancer Treatment

Merck Gains FDA Approval for Endometrial Cancer Treatment

19th June 2024

The FDA has given Merck & Co. additional permission to employ Keytruda for endometrial cancer.


Endometrial carcinoma is the most frequent kind of uterine cancer, accounting for around 67,880 new cases that are projected to be identified in the United States this year.

Keytruda is injected and functions by boosting the body’s immune system’s capacity to identify and combat cancer cells.

The FDA’s most recent choice was reinforced by encouraging findings from the late-stage KEYNOTE-868 trial, which showed that the Keytruda treatment, as opposed to placebo plus carboplatin and paclitaxel after placebo by itself, decreased the likelihood of advancing the disease or mortality by 40% for individuals with cancer that was mismatch repair proficient and by 70% for those with mismatch repair deficient disease.

Dr Gursel Aktan, vice president, Merck Research Laboratories, stated: “This approval represents the first and only anti-PD-1-based option for adult patients with primary advanced or recurrent endometrial carcinoma regardless of mismatch repair status, building on the established role of Keytruda in certain types of advanced endometrial carcinoma as [a] monotherapy and in combination with Lenvima.”

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