NC State study paves the way for next-generation neural implants

Researchers from North Carolina State University have found a way to promote the growth of neural tissue on the surface of biomedical devices, reducing the risk of an implant being rejected.

In a study published on March 12th, a team led by PhD student Lauren Bain examined how nano-scale changes to the surface texture of semiconductor material influenced the development of PC12 cells – used in lab experiments to mimic neurons.

They found very little tissue would adhere to a smooth surface, whereas PC12 cells grew normally when the semiconductors were covered in parallel grooves.

On randomly textured surfaces, the cells thrived, but in unpredictable ways. Finally, on semiconductors covered in nanowires, the tissue grew more quicky – but only 50 per cent of cells spread normally.

According to the researchers, these findings could be used in next-generation neural implants, making them easier to integrate in brain tissue than today's devices.

"[This is] something we can explore as we continue working to develop new biomedical technologies," Ms Bain commented.