New brain research yields fresh insights into SUDEP

Scientists have come a step closer to combating sudden unexpected death in epilepsy (SUDEP) through new research into the functions of the brain.

Published in the Journal of Neuroscience, the University of Iowa study found that stimulation of the amygdala can trigger breathing loss, suggesting this part of the brain plays a key role in regulating this vital function.

Moreover, it was noted that the patients in question were unaware they had stopped breathing – suggesting that instances of SUDEP following seizures may occur for a similar reason.

This is the first time researchers have stimulated the amygdala in humans and reported loss of breathing, with the findings potentially offering a means of reducing instances of SUDEP.

Dr Brian Dlouhy, assistant professor of neurosurgery at the University of Iowa Carver College of Medicine and lead author of the study, said: "Identifying brain areas where seizure spread interferes with breathing may help identify patients at risk for SUDEP and lead to preventive strategies."

It is estimated that SUDEP happens to one in every 1,000 people with epilepsy, and there is currently no way of predicting which individuals will be affected.