TTP Labtech helps to develop new single-cell sequencing approach

TTP Labtech has announced the results of a collaboration with the University of California, San Diego, which aimed to create a new and improved workflow for single-cell sequencing.

Published in the Journal of Laboratory Automation, the workflow was developed through a combination of the university's expertise in genomics and TTP Labtech's Mosquito liquid handlers to miniaturise and automate the process.

TTP Labtech's technology can be used to pipette nanolitre to microlitre volumes with high accuracy and reproducibility, making it possible to miniaturise single-cell RNA library prep reaction setup to minimise sample and reagent requirements.

The resulting workflow was shown to reduce library prep costs by up to 90 percent while maintaining throughput, accuracy and reproducibility, with the ability to distinguish not only between cells at various stages of differentiation, but also between individual cells within each stage.

Joby Jenkins, product manager at TTP Labtech, said: "Reproducibility and sensitivity, as well as scalability and cost, can be limiting factors when large numbers of cells are analysed, and we are very pleased that our partnership with UCSD has achieved our goal of improving sample prep for single cell genomics research."

With over 20 years of experience within the science market, we at Zenopa have the knowledge, skills and expertise to help find the right job for you. To find out more about the current science roles we have available, you can search for the latest job roles, register your details, or contact the team today.